Fig. 1. Global distribution of reported human infections with avian influenza viruses, laboratory-related cases excluded, as of March 2008. Avian H5N1 outbreak records are as of March 2008 and include poultry, and free-living or captive wild birds. Migratory bird flyway configurations after Olsen et al.(2006), based on migration data from Wetlands International for sandpipers, plovers, snipes, and allied taxa of the Order Charidriiformes. Arrows show potential transit routes for H5N1-infected migratory birds from Asia and Europe into the Americas.